C-peptide, liver enzymes and CRP-protein related with vitamin D deficiency in obese and diabetic (type 2) women
Abstract
This study aims to investigate the relationship of vitamin D deficiency and some other biochemical parameters (C-peptide, Alanine transaminase ALT, Aspartate transaminase AST, Alkaline phosphatase ALP and C-reactive protein CRP) levels in obese and diabetic women. The whole sample included 60 women aged 30 – 40 years, divided to three groups (20 women / group) as control, obesity and diabetes groups (the participants in obesity and diabetes groups were diagnosed with vitamin D deficiency). Results revealed: C-peptide increased significantly (p ≤ 0.01 ) in obesity group and not significantly in diabetes group in comparison with the control , ALT increased significantly (p ≤ 0.01 ) in different groups in comparison with the control , AST increased not significantly in different groups in comparison with control, ALP increased significantly (p ≤ 0.01 ) in diabetes group and significantly (p ≤ 0.05 ) in obesity group in comparison with the control, CRP increased significantly (p ≤ 0.01 ) in different groups in comparison with the control. The physiological impacts of these results be discussed according to the impact of vitamin D deficiency that associated with different metabolic and inflammatory disturbances, leading to diverse detrimental influence on the biochemical profiles of the studied groups.
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